IGF-1 LR3 1mg is an IGF-1 analog, and Raw Amino sells it as freeze-dried powder in a 1mg vial. We supply it for in-vitro and laboratory research.
What is IGF-1 LR3?
IGF-1 LR3 is an 83-amino-acid analog of IGF-1 with an arginine swap at position 3 and a 13-amino-acid extension. Those changes stop it binding IGF binding proteins, so it stays active much longer.
It’s widely used in cell culture media.
Why buy IGF-1 LR3 1mg from Raw Amino
Raw Amino keeps IGF-1 LR3 1mg in stock at $230. When you order, you get:
- Free shipping on every order, to any country we deliver to
- New customers save 10% with code firstrawamino$$
- Orders paid in cryptocurrency get 15% off
- Currently in stock; every vial ships sealed and labelled
IGF-1 LR3 mechanism of action
IGF-1 is the hormone that carries out much of growth hormone’s effect on cells. Most of it in the body is bound by IGF binding proteins, which hold it inactive.
LR3 has an arginine in place of glutamate at position 3 plus a 13-residue extension. Binding proteins barely recognize it, so it stays free and active far longer. That’s why it’s the standard IGF-1 in cell culture media.
IGF-1 LR3 1mg product details
- Compound: IGF-1 LR3
- Also known as: Long R3 IGF-1
- CAS number: 946870-92-4
- Molecular formula: C400H625N111O115S9
- Molar mass: 9,111 g/mol
- Structure: 83 amino acids
- Amount: 1mg per vial
- Form: freeze-dried (lyophilized) powder in a sealed glass vial
- SKU: RA-IGF-1-LR3-1MG
- Stock: in stock
- Use: laboratory research only
Published studies on IGF-1 LR3
It was developed for cell culture in the 1990s.
In cell culture it’s several times more potent than IGF-1.
To read the original papers, start with this PubMed search for IGF-1 LR3 at the US National Library of Medicine.
Alternatives to IGF-1 LR3
Where does IGF-1 LR3 fit? It’s an 83-amino-acid IGF-1 analog that avoids binding proteins and lasts for hours. Related options in the Raw Amino catalog:
- MGF is the E-domain peptide from the muscle-specific IGF-1 splice variant
- PEG-MGF is MGF with a PEG chain added so it lasts much longer
- ACE-031 is a soluble activin receptor that soaks up myostatin
- Follistatin-344 is the natural myostatin and activin binding protein
Muscle research splits in two here: IGF-1 and MGF push growth signals up, while ACE-031 and follistatin take the myostatin brake off. See them side by side on our muscle growth peptides page.
Checking your IGF-1 LR3 1mg vial on arrival
Look for the Raw Amino logo, the name of the compound, the Research use only band and the strength, 1mg. Those four things tell you you’ve got the right vial.
Freeze-dried peptide often looks like very little powder, sometimes just a thin white layer. That’s normal. The amount is set by weight, not by how full the vial looks.
Some studies require the lab to confirm identity itself. If yours does, plan for that before reconstituting the whole vial.
Reconstituting IGF-1 LR3 1mg
The concentration is the amount in the vial divided by the volume of water you add. A few common combinations:
- 1mg vial plus 1mL of water: 1mg per mL
- 1mg vial plus 2mL of water: 0.5mg per mL
Use sterile bacteriostatic water and add it slowly against the glass, not straight onto the powder. Swirl or roll the vial until nothing is left at the bottom. Give it a minute or two if it’s slow; never shake it.
Label the vial with the concentration and today’s date before it goes in the fridge.
How to keep IGF-1 LR3 1mg stable
For long-term storage, freeze sealed IGF-1 LR3 1mg at -20°C in the dark. Freeze-dried peptide is stable enough to travel at room temperature for several days.
Mixed solution goes in the fridge between 2 and 8°C and should be used within roughly a month. Keep the other vials sealed and frozen until you need them.
Related muscle growth peptides
- Follistatin-344 1mg: an activin-binding glycoprotein
- ACE-031 1mg: a soluble activin receptor fusion protein
- PEG-MGF 5mg: a pegylated MGF
- MGF 5mg (Mechano Growth Factor): an IGF-1 splice variant peptide
- Ipamorelin 5mg: a GH secretagogue
There’s more in our muscle growth peptides and growth hormone peptides collection, and the Raw Amino home page links to every category.
Common questions about IGF-1 LR3 1mg
How much is in the IGF-1 LR3 1mg vial?
1mg of freeze-dried IGF-1 LR3. The amount is printed on the label.
Is IGF-1 LR3 1mg in stock?
Yes. It’s in stock now.
Do you ship internationally?
Yes. Raw Amino ships to customers around the world at no charge.
Is there a discount code?
Yes. New customers can use firstrawamino$$ for 10% off, and crypto payments get 15% off at checkout.
What do I mix IGF-1 LR3 1mg with?
Sterile bacteriostatic water. The mixing chart above shows the concentration you get from each volume.
Order IGF-1 LR3 1mg from Raw Amino
IGF-1 LR3 1mg is in stock at $230. Add it to your cart, enter firstrawamino$$ for 10% off your first order, and it ships free.
Other compounds for this kind of work are in our muscle growth peptides and growth hormone peptides.
Raw Amino sells this product for laboratory research only. It isn’t for human or veterinary use, and these statements haven’t been evaluated by the FDA.





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