Buy MGF 5mg online from Raw Amino as a sealed, freeze-dried vial. It’s an IGF-1 splice variant peptide, supplied in a 5mg vial. It’s sold for laboratory research only.
MGF (mechano growth factor) explained
Mechano growth factor is a version of IGF-1 that muscle makes after mechanical load or damage. It comes from alternative splicing of the IGF-1 gene and is called IGF-1Ec in humans. The research peptide is a synthetic copy of its unique E-domain tail, 24 amino acids long.
Geoffrey Goldspink’s group at the Royal Free Hospital in London described it in the 1990s and gave it the name.
Ordering MGF 5mg online at Raw Amino
Raw Amino keeps MGF 5mg in stock at $60. When you order, you get:
- Free worldwide shipping, with no minimum order
- New customers save 10% with code firstrawamino$$
- Orders paid in cryptocurrency get 15% off
- Currently in stock; every vial ships sealed and labelled
How MGF works
When muscle is stretched or damaged, the IGF-1 gene is spliced differently and makes MGF first, before the main IGF-1 form. The idea is that MGF’s E-domain wakes up satellite cells, the muscle stem cells that repair fibers.
The synthetic E-peptide has no IGF-1 receptor binding domain, so any effect it has is meant to come through a different, still unidentified route. Free MGF peptide also breaks down within minutes, which is why a pegylated version exists.
MGF 5mg product details
- Compound: MGF (mechano growth factor)
- Also known as: mechano growth factor, IGF-1Ec E-peptide
- Molecular formula: C121H200N42O39
- Sequence: Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-His-Lys
- Amount: 5mg per vial
- Form: freeze-dried (lyophilized) powder in a sealed glass vial
- SKU: RA-MGF-5MG
- Stock: in stock
- Use: laboratory research only
What the research says about MGF
Yang and Goldspink reported in FEBS Letters in 2002 that the MGF E-peptide made muscle satellite cells divide more, separately from the main IGF-1 receptor.
Later studies looked at it in heart and nerve injury models. Some groups couldn’t reproduce every result, so the field still argues about how much of it acts on its own. All of the work is in cells and animals.
To read the original papers, start with this PubMed search for MGF at the US National Library of Medicine.
MGF vs related compounds
In short, MGF is the E-domain peptide from the muscle-specific IGF-1 splice variant. Here’s how its closest relatives differ:
- Follistatin-344 is the natural myostatin and activin binding protein
- IGF-1 LR3 is an 83-amino-acid IGF-1 analog that avoids binding proteins and lasts for hours
- PEG-MGF is MGF with a PEG chain added so it lasts much longer
- ACE-031 is a soluble activin receptor that soaks up myostatin
Muscle research splits in two here: IGF-1 and MGF push growth signals up, while ACE-031 and follistatin take the myostatin brake off. See them side by side on our muscle growth peptides page.
How to mix MGF 5mg
The concentration is the amount in the vial divided by the volume of water you add. A few common combinations:
- 5mg vial plus 1mL of water: 5mg per mL
- 5mg vial plus 2mL of water: 2.5mg per mL
- 5mg vial plus 3mL of water: 1.67mg per mL
Most labs use sterile bacteriostatic water. Let the sealed vial come to room temperature, then run the water slowly down the inside of the glass and roll the vial gently until it’s clear. Shaking makes foam and can damage the peptide, so don’t.
Label the vial with the concentration and today’s date before it goes in the fridge.
MGF 5mg storage and shelf life
Sealed MGF 5mg vials keep best in a freezer at -20°C, away from light. Short spells at room temperature during shipping are fine for freeze-dried peptide.
Mixed solution goes in the fridge between 2 and 8°C and should be used within roughly a month. Keep the other vials sealed and frozen until you need them.
What is printed on the MGF 5mg vial
The Raw Amino label is easy to read: our logo at the top, the product name in large type, a purple band that says Research use only, and the vial strength (5mg). If anything on it is unclear or damaged, email us before you open the vial.
The powder inside should look like a small dry cake or loose white flakes at the bottom of the glass. It’s normal for it to shift around in transit or to sit as a thin film on the side of the vial.
Some studies require the lab to confirm identity itself. If yours does, plan for that before reconstituting the whole vial.
Related muscle growth peptides
- ACE-031 1mg: a soluble activin receptor fusion protein
- Follistatin-344 1mg: an activin-binding glycoprotein
- PEG-MGF 5mg: a pegylated MGF
- IGF-1 LR3 1mg (Receptor Grade): an IGF-1 analog
- GHK-Cu 50mg: a copper peptide
Compare more options in the muscle growth peptides and healing and recovery peptides range or go back to the Raw Amino shop.
MGF 5mg FAQ
How much is in the MGF 5mg vial?
5mg of freeze-dried MGF. The amount is printed on the label.
Do you ship internationally?
Yes. Raw Amino ships to customers around the world at no charge.
Is there a discount code?
Yes. New customers can use firstrawamino$$ for 10% off, and crypto payments get 15% off at checkout.
What do I mix MGF 5mg with?
Sterile bacteriostatic water. The mixing chart above shows the concentration you get from each volume.
How should I store MGF 5mg?
Freeze sealed vials at -20°C. Once mixed, keep it at 2 to 8°C in the fridge and use it within about four weeks.
Get MGF 5mg with free shipping
Ready to order? MGF 5mg costs $60 with free worldwide shipping. First-time buyers save 10% with code firstrawamino$$.
Need more for the same project? Look through the muscle growth peptides and healing and recovery peptides.
Raw Amino sells this product for laboratory research only. It isn’t for human or veterinary use, and these statements haven’t been evaluated by the FDA.
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